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File:Computational-and-Experimental-Characterization-of-dVHL-Establish-a-Drosophila-Model-of-VHL-Syndrome-pone.0109864.s005.ogv

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English: The eye defect caused by over-expression of SIMA is suppressed by co-expression of either dVHL, pVHL19, or pVHL30 at 29°C. 1. GMR-Gal4; UAS-SIMA; UAS-RFP (no hatching). 2. GMR-Gal4; UAS-SIMA; UAS-dVHL. 3. GMR-Gal4; UAS-SIMA; UAS-pVHL19. 4. GMR-Gal4; UAS-SIMA; UAS-pVHL30. At 29°C over expression of SIMA by GMR-Gal 4 caused pupal lethality (1) that could be rescued by co-expression of either dVHL, pVHL19 or pVHL30 (evidenced as flies motility 2–4).
Date
Source Movie S1 from Shmueli M, Schnaider L, Herzog G, Gazit E, Segal D (2014). "Computational and Experimental Characterization of dVHL Establish a Drosophila Model of VHL Syndrome". PLOS ONE. DOI:10.1371/journal.pone.0109864. PMID 25310726. PMC: 4195687.
Author Shmueli M, Schnaider L, Herzog G, Gazit E, Segal D
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